Antibacterial medication with combined action

Augmentin is an antibacterial agent, a combination of a bactericidal antibiotic — Amoxicillin and a beta-lactamase inhibitor — Clavulanic acid. This effective combination for treating bacterial infections was developed in 1977-1978 by british scientists working at Beecham (now it’s the part of GlaxoSmithKline). Augmentin is the original name and used by its inventors.

One of the active substances of it - Amoxicillin - is a semi-synthetic antibiotic of the penicillin group of a wide spectrum of actions. Augmentin is used to treat many bacterial infections, such as: middle ear infection, tonsillitis, pneumonia, and urinary tract infections. You can order Augmentin in our pharmacy at a low price.

How does Augmentin work?

Amoxicillin belongs to the penicillin class. They are organic compounds, the basis of which is 6-aminopenicillanic acid, which is obtained from the cultures of the mold Penicillium chrysogenum.

Amoxicillin — an antibacterial bactericidal acid-resistant agent of a wide spectrum of action from the group of semi-synthetic penicillins. It disrupts the synthesis of peptidoglycan (a component of the bacterial cell wall) during division and growth, and causes bacterial lysis.  Active against aerobic gram-positive bacteria: Staphylococcus spp. (with the exception of strains producing penicillinase), Streptococcus spp., and aerobic gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Klebsiella spp.

The second active substance of Augmentin, Clavulin acid is a beta-lactamase inhibitor. It has its own antibacterial activity and it stimulates antimicrobial immunity. Clavulin acid is able to bind to penicillin-binding proteins of gram-positive and gram-negative bacteria and do lysis of the bacterial wall.

How to use Augmentin?

Augmentin is available in the form of tablets for oral administration and injections for intravenous infusion. You can order Augmentin in our pharmacy in a form and dosage best for your treatment.

The area of application of Augmentin is wide and includes many bacterial infections caused by sensitive microflora: upper respiratory tract infections (bronchitis, pneumonia, pleural empyema), ENT infections (sinusitis, tonsillitis, otitis media), biliary tract infections (cholangitis, cholecystitis); intestinal infections (dysentery, salmonellosis, salmonella carriage); infections of the genitourinary system and pelvic organs (pyelonephritis, pyelitis, cystitis, urethritis, prostatitis, cervicitis, salpingitis, endometritis, postpartum sepsis, pelvioperitonitis, soft chancre, goncroid); infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses, abscess, phlegmon, wound infection); osteomyelitis;  endocarditis; meningitis; sepsis; peritonitis; postoperative infections; and many others.

The exact dosage and treatment regimen for Augmentin should be prescribed by the attending physician, depending on the type of disease, its severity and the patient's individual response to the active substances. When taking Augmentin or other antibiotics, it is important to strictly follow the prescribed treatment regimen, even if the symptoms of the disease have already passed.

What contraindications Augmentin has?

Among the main contraindications for taking this drug are hypersensitivity to amoxicillin and other antibiotics of the penicillin group and hypersensitivity to clavulanic acid, as well as allergic diathesis, bronchial asthma, pollinosis, infectious mononucleosis, liver failure, a history of gastrointestinal tract diseases (especially colitis associated with the use of antibiotics).

Side effects and symptoms of overdose are manifested by nausea, vomiting and diarrhea. A complete list of side effects can be found in the official instructions when ordering Augmentin in our pharmacy.